<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:sy="http://purl.org/rss/1.0/modules/syndication/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:googleplay="http://www.google.com/schemas/play-podcasts/1.0" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:podcast="https://podcastindex.org/namespace/1.0"><channel><generator>Alitu</generator><title><![CDATA[The Spiraling List of Indignities]]></title><description><![CDATA[Two middle-aged guys, two microphones and a lot of aches and pains. Join us, John and Chuck, as we navigate middle age, our crumbling physicality and the mounting list of indignities that continue to disappoint us. Each week, we’ll talk about men’s health, supplements, physical therapy, fitness, nutrition, sleep, medical research and whatever else we hope will stave off the inevitable. Join the conversation at r/SpiralingList.]]></description><itunes:summary><![CDATA[Two middle-aged guys, two microphones and a lot of aches and pains. Join us, John and Chuck, as we navigate middle age, our crumbling physicality and the mounting list of indignities that continue to disappoint us. Each week, we’ll talk about men’s health, supplements, physical therapy, fitness, nutrition, sleep, medical research and whatever else we hope will stave off the inevitable. Join the conversation at r/SpiralingList.]]></itunes:summary><language>en-gb</language><podcast:medium>podcast</podcast:medium><podcast:location rel="creator" country="US">Kentucky</podcast:location><podcast:podping usesPodping="true"></podcast:podping><podcast:guid>b3eb8d55-7f09-5f80-9ffc-be305f9fbacc</podcast:guid><link>https://www.reddit.com/r/SpiralingList/</link><atom:link href="https://feeds.alitu.com/7116276" rel="self" type="application/rss+xml"></atom:link><itunes:type>serial</itunes:type><itunes:owner><itunes:email>SpiralingList@gmail.com</itunes:email><itunes:name>Chuck and John</itunes:name></itunes:owner><itunes:author>Chuck and John</itunes:author><podcast:person>Chuck and John</podcast:person><itunes:explicit>true</itunes:explicit><itunes:image href="https://feeds.alitu.com/7116276/d72b2c89-b673-48b3-9b36-229139198f6a.jpg?t=1786573392000"></itunes:image><podcast:locked>Yes</podcast:locked><itunes:category text="Health &amp; Fitness"></itunes:category><itunes:category text="Comedy"></itunes:category><itunes:category text="Health &amp; Fitness"><itunes:category text="Mental Health"></itunes:category></itunes:category><item><guid isPermaLink="false">6be03e65-31c5-45a5-8f28-0e70289ceb7a</guid><itunes:title><![CDATA[Dusk to Dawn - Part 2]]></itunes:title><title><![CDATA[Dusk to Dawn - Part 2]]></title><description><![CDATA[<p>In this week's episode we observe the 50-something year old male's morning routine. It ain't pretty, but we're just happy to still be above ground. We hope you enjoy! NOTE: Apologies in advance for a few small audio problems in this episode. On the upside, they're very short, just a few seconds apiece.</p><p>Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p><p>Links on this week’s show:</p><ul><li>New Yorker Rachel Aviv, "Mary Had Schizophrenia—Then Suddenly She Didn't," July 21, 2025 (print issue July 28): <a href="https://www.newyorker.com/magazine/2025/07/28/mary-had-schizophrenia-then-suddenly-she-didnt" target="_blank">LINK</a></li><li>NPR "Population decline means fewer caregivers for the elderly," November 2, 2025: <a href="https://www.npr.org/2025/11/02/nx-s1-5535648/population-elderly-caregivers" target="_blank">LINK</a></li></ul>]]></description><pubDate>Sat, 05 Sep 2026 13:57:19 GMT</pubDate><itunes:duration>01:04:22</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/6be03e65-31c5-45a5-8f28-0e70289ceb7a.mp3?t=1788616640000" length="61800648" type="audio/mpeg"></enclosure><itunes:episodeType>full</itunes:episodeType><itunes:season>1</itunes:season><podcast:season>1</podcast:season><itunes:episode>5</itunes:episode><podcast:episode>5</podcast:episode><itunes:explicit>true</itunes:explicit><itunes:author>Chuck and John</itunes:author></item><item><guid isPermaLink="false">0b91a877-e093-499f-b935-59d7df294188</guid><itunes:title><![CDATA[Dusk to Dawn - Part 1]]></itunes:title><title><![CDATA[Dusk to Dawn - Part 1]]></title><description><![CDATA[<p>Join us as we explore the nocturnal habits of the 50-something year old male, with all the indignities that this entails. A little depressing, sure, but it beats the alternative! :)</p><p>Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p><p>Links from this week’s show:</p><ul><li>Nature lithium/Alzheimer's paper. Aron, L. et al. "Lithium deficiency and the onset of Alzheimer's disease." <em>Nature</em>, Aug 6, 2025. <a href="https://www.nature.com/articles/s41586-025-09335-x" target="_blank">LINK</a> Harvard Medical School write-up: <a href="https://hms.harvard.edu/news/could-lithium-explain-treat-alzheimers-disease" target="_blank">LINK</a> NIH plain-language: <a href="https://www.nih.gov/news-events/nih-research-matters/lithium-levels-tied-alzheimers-disease-dementia" target="_blank">LINK</a></li><li>Mouthwash/diabetes study: Joshipura KJ et al. "Over-the-counter mouthwash use and risk of pre-diabetes/diabetes." <em>Nitric Oxide</em>, 2017;71:14–20. DOI: 10.1016/j.niox.2017.09.004: PubMed: <a href="https://pubmed.ncbi.nlm.nih.gov/28939409/" target="_blank">LINK</a> British Dental Journal commentary: <a href="https://www.nature.com/articles/sj.bdj.2018.1020" target="_blank">LINK</a></li><li>Harvard isolation study. Analysis published July 15, 2026 in <em>Journal of Personality and Social Psychology</em> — 11 pooled aging studies, 175,070 adults 50+, 18 countries. Loneliness linked to cognitive decline and earlier death independent of social isolation: <a href="https://www.health.harvard.edu/healthy-aging-and-longevity/loneliness-linked-to-cognitive-decline-and-early-death" target="_blank">LINK</a></li></ul>]]></description><pubDate>Sat, 29 Aug 2026 19:55:26 GMT</pubDate><itunes:duration>00:57:29</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/0b91a877-e093-499f-b935-59d7df294188.mp3?t=1788033327000" length="55193839" type="audio/mpeg"></enclosure><itunes:episodeType>full</itunes:episodeType><itunes:season>1</itunes:season><podcast:season>1</podcast:season><itunes:episode>4</itunes:episode><podcast:episode>4</podcast:episode><itunes:explicit>true</itunes:explicit><itunes:author>John and Chuck</itunes:author></item><item><guid isPermaLink="false">71d4bc2b-38d4-4e44-8321-10b308fdeec9</guid><itunes:title><![CDATA[Pills, Potions and Palliatives - Part 2]]></itunes:title><title><![CDATA[Pills, Potions and Palliatives - Part 2]]></title><description><![CDATA[<p>Part 2 of pills, potions and palliatives. NOTE: I accidentally mangled the first version of this episode, this is an updated take with all of the segments included. :) In this week's episode you can hear about the fistful of supplements that Chuck is taking in hopes of delaying the inevitable. If nothing else, he can serve as an example of what NOT TO DO in your own life. We hope you enjoy!</p><p>Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p><p>Links on this week’s show:</p><ul><li>Alleviation By Fisetin Of Frailty, Inflammation, And Related Measures In Older Women: <a href="https://www.mayo.edu/research/clinical-trials/cls-20438802" target="_blank">LINK</a></li><li>Fisetin is a senotherapeutic that extends health and lifespan: <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6197652/?utm_source=chatgpt.com" target="_blank">LINK</a></li><li>Telomere Length and Biological Aging: The Role of Strength Training in 4814 US Men and Women: <a href="https://www.mdpi.com/2079-7737/13/11/883" target="_blank">LINK</a></li></ul>]]></description><pubDate>Sun, 23 Aug 2026 15:57:24 GMT</pubDate><itunes:duration>01:06:30</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/71d4bc2b-38d4-4e44-8321-10b308fdeec9.mp3?t=1787500645000" length="63842378" type="audio/mpeg"></enclosure><itunes:episodeType>full</itunes:episodeType><itunes:season>1</itunes:season><podcast:season>1</podcast:season><itunes:episode>3</itunes:episode><podcast:episode>3</podcast:episode><itunes:explicit>true</itunes:explicit><itunes:author>John and Chuck</itunes:author></item><item><guid isPermaLink="false">1f4e5892-e50e-488f-8b02-901dd2160b1e</guid><itunes:title><![CDATA[Pills, Potions and Palliatives - Part 1]]></itunes:title><title><![CDATA[Pills, Potions and Palliatives - Part 1]]></title><description><![CDATA[<p>In our second episode you can be bored to tears while hearing about the pills, concoctions and duct tape we use to try to hold it all together. Less aches and pains? Probably not. Increased longevity? Doubtful. Expensive pee... guaranteed. Part 1 explores John's stack. Enjoy!</p><p>Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p><p>Links on this week’s show:</p><ul><li>FDA Approves First Vagus Nerve Stimulation Device for Rheumatoid Arthritis: <a href="https://www.medscape.com/viewarticle/fda-approves-first-vagus-nerve-stimulation-device-rheumatoid-2025a1000keb" target="_blank">LINK</a></li><li>Historical changes in the mineral content of fruit and vegetables in the UK from 1940 to 2019: <a href="https://pubmed.ncbi.nlm.nih.gov/34651542/" target="_blank">LINK</a></li><li>Declining Fruit and Vegetable Nutrient Composition: What Is the Evidence? <a href="https://journals.ashs.org/view/journals/hortsci/44/1/article-p15.xml?utm_source=chatgpt.com" target="_blank">LINK</a></li></ul>]]></description><pubDate>Sun, 16 Aug 2026 02:42:44 GMT</pubDate><itunes:duration>00:59:41</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/1f4e5892-e50e-488f-8b02-901dd2160b1e.mp3?t=1786848165000" length="57302067" type="audio/mpeg"></enclosure><itunes:episodeType>full</itunes:episodeType><itunes:season>1</itunes:season><podcast:season>1</podcast:season><itunes:episode>2</itunes:episode><podcast:episode>2</podcast:episode><itunes:explicit>true</itunes:explicit><itunes:author>John and Chuck</itunes:author></item><item><guid isPermaLink="false">43296927-453d-4b57-a0de-471caa81aaa6</guid><itunes:title><![CDATA[Body by Sisyphus]]></itunes:title><title><![CDATA[Body by Sisyphus]]></title><description><![CDATA[<p>Move or rust! In this first episode we dig into what we're doing, as 50 year old guys, to stay active. The goal is a thin veneer of fitness as we stumble into our dotage. Will we make it... probably not. If you're a 20 or 30-something year old all of this will be completely foreign to you and may make you sad. Enjoy!</p><p>Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p><p>Links on this week’s show:</p><ul><li>FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain: <a href="https://www.fda.gov/news-events/press-announcements/fda-approves-novel-non-opioid-treatment-moderate-severe-acute-pain" target="_blank">LINK</a></li><li>Vitamin B3 can help protect against skin cancer: <a href="https://www.npr.org/2025/09/17/nx-s1-5544145/vitamin-b3-can-help-protect-against-skin-cancer-heres-who-may-benefit" target="_blank">LINK</a></li></ul>]]></description><pubDate>Sat, 15 Aug 2026 15:58:48 GMT</pubDate><itunes:duration>01:04:01</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/43296927-453d-4b57-a0de-471caa81aaa6.mp3?t=1786809529000" length="61465470" type="audio/mpeg"></enclosure><itunes:episodeType>full</itunes:episodeType><itunes:season>1</itunes:season><podcast:season>1</podcast:season><itunes:episode>1</itunes:episode><podcast:episode>1</podcast:episode><itunes:explicit>true</itunes:explicit><itunes:author>John and Chuck</itunes:author></item><item><guid isPermaLink="false">3d545728-8b15-4643-8734-7ef7834c62f3</guid><itunes:title><![CDATA[Trailer - The Spiraling List of Indignities]]></itunes:title><title><![CDATA[Trailer - The Spiraling List of Indignities]]></title><description><![CDATA[<p>Welcome to The Spiraling List of Indignities: two 50-something year old guys, two microphones, and an endless supply of gripes and strategies to forestall the inevitable. It may be the only catharsis you get all week! Join the conversation and share your own experiences at <a href="https://reddit.com/r/SpiralingList" target="_blank">reddit.com/r/SpiralingList</a></p>]]></description><podcast:location rel="creator" country="US">Kentucky</podcast:location><pubDate>Thu, 13 Aug 2026 16:46:08 GMT</pubDate><itunes:duration>00:00:44</itunes:duration><enclosure url="https://feeds.alitu.com/7116276/3d545728-8b15-4643-8734-7ef7834c62f3.mp3?t=1786639569000" length="709811" type="audio/mpeg"></enclosure><itunes:episodeType>trailer</itunes:episodeType><itunes:author>Chuck and John</itunes:author></item></channel></rss>